This was me this morning!! (& many others) If you’re using mods from the Mod List, disable those. That’s the only thing that worked for me, I was about to rip my hair out.
I tried rolling back today’s new NVIDIA GPU update to the last version, and I uninstalled the Nexus mods I manually added to my mods folder earlier. Those are literally the only things that changed between when I exited and relaunched the game. Oh & the first thing I did was try to clear the PSO cache of course, from the crash popup message and then again through the Steam settings